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Todays approval represents a significant step forward in enabling children to be treated with Brineura as early as possible, when we can have the greatest impact in altering the natural course of disease, Hank Fuchs, president of worldwide research and development at BioMarin, said in a statement
However, there is still uncertainty regarding the generalizability of specific strains to a population as a whole, as the study used a population of homogenous mice
The primary research outcome was the severity of depressive disorder which was assessed using the second version of the Beck Depression Inventory-II (BDI-II), and a 50% reduction of the baseline BDI score was considered as the treatment response
Retatrutide, a triple agonist against GLP-1, GIP and glucagon receptors, has demonstrated significant weight loss (up to a 24% reduction in body weight at the highest dose) and metabolic benefits in people with obesity, both with and without type 2 diabetes in phase 2 clinical trials
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