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High adoption across gyms and wellness centers in So Paulo, Rio de Janeiro, Braslia, and Porto Alegre reflects rising demand for antioxidant support, muscle recovery, and vascular-performance benefits

Training sessions were withheld during this treatment period to prevent potential training interference from residual semaglutide effects its long half-life

Timing of fluid intake affects both hydration and digestive comfort

Semaglutide is recommended as an option: As monotherapy when metformin is contraindicated or not tolerated, or In dual or triple therapy combinations when a GLP-1 receptor agonist is appropriate (for example, when further glucose control is needed and weight loss would be beneficial, or when other treatments are unsuitable)