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Using preclinical models of breast cancer, the team also found they could slow tumor growth by blocking the cancer's ability to use glutathione

Initial assessment should include a detailed history characterizing the joint symptoms: onset relative to medication initiation, location and pattern of joint involvement, severity and functional impact, aggravating and relieving factors, and any associated symptoms such as swelling, redness, or morning stiffness

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The facial features associated with the syndrome might include narrower head at the temples (narrow frontal diameter), almond-shaped eye openings, thin upper lip, and downturned mouth corners