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MASH and ALD share several similarities, including excess intake of nutrients or ethanol, and the pathological features of hepatic steatosis, inflammation and fibrosis 5,6
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You cannot simply resume your previous dose without risking severe side effects
Collectively, these trends emphasize the central roles of polarity, flexibility, and molecular size in shaping the absorption potential and reinforce the predictive power of in silico ADME models when interpreted in the SAR framework
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