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Common side effects include: Constipation Decreased appetite Diarrhea Nausea Vomiting Researchers reported that these side effects were usually mild to moderate and most commonly occurred during the dose-escalation phase of treatment

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Research protocols explore combination approaches with other senolytic compounds such as dasatinib and quercetin, providing frameworks for studying multi-target senolytic strategies and understanding synergistic effects in various experimental models and disease research applications