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Nitric oxide and cyclic GMP in cell signaling and drug development

Its primary role is to regulate blood sugar levels by stimulating insulin release from the pancreas in a glucose-dependent manner, significantly reducing the risk of low blood sugar episodes (hypoglycemia)

Madaio was corresponding author of a study this summer also in Kidney International that showed that using the same antibody, this time to deliver the anti-inflammatory protein kinase C-alpha inhibitor directly to the kidney, enabled the organs recovery in a similar model of nephritis

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