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Thats especially important for PIs building proof-of-concept work

Participants treated with liraglutide (239), semaglutide (240), or tirzepatide (200) in the clinical trials had a percent reduction in fat mass approximately three times greater than the reduction in lean mass, leading to an overall improvement in body composition

This is also seen in medications for depression (SSRIs), which increase serotonin to help regulate mood and are known to cause low libido and delayed/anorgasmia as well

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