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There is a separate type of steatosis by which phospholipid accumulation leads to a pattern similar to the diseases with inherited phospholipid metabolism defects (e.g., TaySachs disease) Causes: (a) Microvesicular: Aspirin (Reye's syndrome), ketoprofen, tetracycline (especially if expired) (b) Macrovesicular: Acetaminophen, methotrexate (c) Phospholipidosis: Amiodarone, total parenteral nutrition (d) Antiviral: nucleoside analogues (e) Corticosteroid (f) Hormonal: Tamoxifen Granuloma [edit] Drug-induced hepatic granulomas are usually associated with granulomas in other tissues and patients typically have features of systemic vasculitis and hypersensitivity

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Supplementation with brain-supporting nutrients including B12, either as oral supplements or sublingual forms, can address this cause of fatigue

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At the end of the experiment, the food intake had decreased by about 20% in all three groups of tumor-bearing mice, which showed that low- or high-dose L-carnitine treatment did not improve the anorexia associated with cachexia

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