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Position 34 lysine is replaced with arginine, freeing the original Lys-26 position to serve as the unique site for fatty-acid attachment
de Lira-Garcia, C., Souto-Gallardo, M., Bacardi-Gascon, M., and Jimenez-Cruz, A
For perspective, prior to 2023, the top-selling drugs were largely immunology or oncology biologics (like Humira, Keytruda, Eliquis), but by mid-2024, the list transformed GLP-1 agonists entered the top ranks
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