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Concurrent nutritional deficienciesparticularly folate or iron deficiencycan impair the response to B12 treatment, as these nutrients work together in red blood cell production

Interestingly, most people are deficient in vitamin B12, especially vegetarians or vegans, and persons with specific diseases

Signs and symptoms of vitamin B12 deficiency signs may include: Weakness or fatigue Pale skin Appetite loss Weight loss Palpitations Numbness and tingling Poor concentration Infertility Depression Memory impairment Sore mouth or tongue Disturbed sleep Frequent infections What are the side effects of a B12 shot