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The attention around retatrutide is not just a trend but is actually backed up by science and clinical trials

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Additionally, if you are using insulin or sulfonylureas, the risk of hypoglycaemia may increase when starting tirzepatide, so discuss potential dose adjustments with your diabetes team

2019 tested dulaglutide in 20 healthy volunteers and found no significant change in 24-hour urinary free cortisol, dexamethasone suppression, or ACTH stimulation