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Note what is absent from both lists: weight loss

Any new or concerning cardiac symptoms warrant appropriate clinical evaluation to exclude other causes, regardless of their temporal relationship to medication initiation

Current studies also believe that targeted TMAO and its metabolic pathway may potentially possess therapeutic value in various diseases

In the Phase 2 obesity trial it produced about 24% weight loss at 12 mg over 48 weeks, the most of any drug in the class, and it cut liver fat by 86% in the people who started with fatty liver. In the 80-week Phase 3 obesity trial of 2,300 adults with an average BMI of 40, 12 mg produced 28% weight loss and 9 mg reached 26%