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A meta-analysis of 8 RCTs found that NAC supplementation significantly reduced fasting glucose (WMD: -5.84 mg/dL) and HbA1c (WMD: -0.27%) in people with metabolic conditions (Sarkaki et al., Clin Nutr ESPEN, 2021) [57]
J Biol Chem , 278: 1460714613, 2003
Pharmacokinetic studies using radiolabeled versions of the peptide reveal rapid absorption after injection, with peak concentrations achieved within 3 to 6 minutes following intramuscular administration
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