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Dufes and colleagues reported the first glucose transporter-targeted drug delivery system
Mild-to-moderate hypoglycemia is more common and easily treated compared with severe episodes requiring medical assistance
Clinical trial enrollment for retatrutide follows the same BMI pattern: 30 or higher, or 27 or higher with comorbidities
It now includes oral GLP-1 drugs, amylin combinations, dual agonists, triple agonists, long-acting platforms, and differentiated assets designed for durability, tolerability, access, or broader metabolic indications
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