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This is now possible using bisulfite conversion combined with the next-generation sequencing (BS-Seq), which enables strand-specific and single-base resolution profiling of both CG and non-CG methylation (Cokus et al., 2008

Glutathione Synthesis

Dynamic control by PcG and TrxG group Members of the PcG complex catalyze trimethylation of lysine 27 of histone 3 (H3K27me3), which leads to transcriptional repression through local heterochromatin formation (for review, see Cedar and Bergman (2009)) and/or inhibition of transcriptional elongation through stalling of RNA polymerase II (Stock et al., 2007)

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