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By year four, fewer than half of those who achieved clinically significant loss had maintained it
Depending on how long youve been off of the medication, you may notice an uptick in hunger and side effects, like nausea
Clinical trials show diarrhea typically peaks during dose escalation and often resolves within 48 weeks as the body adapts, though some patients experience persistent symptoms requiring dose adjustment or medication formulation changes
Ethics declarations Competing interests Author 2 (Marcel H.A
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