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Meal Timing & Frequency: The Small Meal Strategy Given that GLP-1s slow digestion and promote early fullness, shifting away from the traditional three large meals a day is often beneficial

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This is particularly important if these inhibitors are shown to affect bone metabolism through independent mechanisms beyond glucose control

A 2.5 mg starting dose of tirzepatide is roughly equivalent in clinical effect to a 0.25 mg starting dose of semaglutide, not because one is weaker, but because the molecular pharmacology demands different quantities to achieve similar receptor occupancy