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Many men report visible improvements in body composition within 4 to 8 weeks, though individual results depend on training consistency, nutrition, and sleep quality

Avoidant/Restrictive Food Intake Disorder (ARFID) ARFID involves a severe pattern of avoiding certain foods or selective eating that results in failure to meet nutritional needs without the body shape or body weight concerns central to anorexia nervosa

TrpC5 mediates acute leptin and serotonin effects via pomc neurons

More serious risks include pancreatitis, gallbladder disease, acute kidney injury from dehydration, and hypoglycemia (when used with insulin or sulfonylureas)