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Dillon et al., in a phase I clinical trial, evaluated a vaccine containing nine breast-cancer-associated peptides (MHC I restricted) from MAGE-A1, 3A3, and AA10 proteins, CEA, NY-ESO-1, and HER2/neu along with a TLR3 agonist, Poly-ICLC, and an adjuvant derived from tetanus toxin

This inherent stability allows it to remain biologically active for extended periods, a characteristic that makes it suitable for oral administration in research settings, particularly for studies focused on gastrointestinal health

(2019) investigated the long-term effects of stroke over a time period of about 15 months