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The drugs mimic GLP-1, a hormone the body produces after eating, which can decrease appetite and help the body manage insulin production
Heaematoxylin- and eosin-stained sections were scored by a histopathologist blinded to treatment allocation using the Nonalcoholic Activity Score 70 with fat scored 03, ballooning 02, and lobular inflammation 02
Furthermore, in some tumours, the need for methyl groups for epigenetic regulation prevents activation of the trans-sulphuration pathway for cysteine synthesis, instead prioritising one-carbon metabolism
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