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Rat full-thickness wounds (6mm diameter, 13-day study) treated with GHK showed 64.5% reduction in wound size compared to 45.6% for vehicle-treated and 28.2% for control group, accompanied by significantly lower TNF- and elastin-degrading MMPs

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To combat oxidative stress, most organisms boost the activity of enzymes like superoxide dismutase (SOD) and glutathione peroxidase, or they work to decrease the concentration of the lipid breakdown product malondialdehyde (MDA) (100, 101)

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