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20 mg vial Concentration: 20 mg 3 mL = 6.667 mg/mL (equivalently 6,667 mcg/mL) Dose in mg: 250 mcg = 0.25 mg Draw volume: 0.25 mg 6.667 mg/mL = 0.0375 mL Syringe units: 0.0375 mL 100 = 3.75 units 4 units on a U-100 syringe On the 20 mg vial, one documented dose is a very small draw about the 4-unit mark

The limited human evidence includes: A randomised double-blind placebo-controlled Phase 2 enema trial in ulcerative colitis with 53 participants, published only as a meeting abstract

Injections bypass the gut and correct deficiency

When people think a medicine is pricey, they frequently report benefits, even when its actually an inert substance