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These may include constipation, vomiting, and abnormally high hemoglobin levels
That can mean type 2 diabetes, high blood pressure (hypertension), or high cholesterol
Semaglutide slows gastric emptying, and adequate hydration supports digestion, helps prevent constipation, and reduces the risk of kidney issues from dehydration
That same biology also defines the constraints as low bioavailability requires strict administration conditions, higher doses, and can introduce exposure variability driven by differences in gastric pH, emptying time, and intestinal absorption
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