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Inflammatory mediators can cross the bloodbrain barrier, activating the microglia and leading to the release of neurotoxic factors with adverse effects on dopaminergic neurons [21]

Citraro R, Leo A, Marra R et al (2015) Antiepileptogenic effects of the selective COX-2 inhibitor etoricoxib, on the development of spontaneous absence seizures in WAG/Rij rats

Thyroid disorders, for example, slow metabolism and reduced energy production, can cause persistent tiredness

Encapsulation and Redox Ratio Control : A commercially viable API must achieve an encapsulation efficiency of 70% or higher to justify the supplements cost and performance