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It begins with the formation of atheromatous plaque, which is triggered by endothelial ROS generation and accumulation of LDL in the intima
That means for every 10 pounds lost, 2.5 to 4 pounds comes from muscle
All NMOSD are classified (according to the leading pathophysiological mechanisms) into diseases with identifiable antibodies against aquaporin 4 AQP4-IgG (NMOSD-AQP4), NMOSD without AQP4-IgG or with unknown AQP4-IgG status and NMOSD with identified antibodies against Myelin Oligodendrocyte Glycoprotein, (NMOSD-MOG)
Subsequently, leveraging the superpopulation label and PCs of the 1000 Genome individuals, we train a K -nearest neighbors model to assign genetic ancestry labels to each ATLAS individual
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