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Jasmonates and octadecanoids: signals in plant stress responses and plant development
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Although co-expression relationships do not establish causality, integrating module connectivity, hub-gene centrality, and network topology with ML frameworks improves the prioritization of candidate regulators for experimental validation and metabolic engineering ( Beyond co-expression, understanding how flavonoid regulatory hierarchies shift during stress adaptation requires approaches capable of inferring directional relationships among genes, metabolites, and signaling pathways
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