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It becomes readily available for the body to use
Discussing realistic expectations early can prevent frustration later
Recent research suggests that without lifestyle support, such as strength training and adequate protein intake, patients on GLP-1s can lose up to 40 percent of their total body weight, primarily from lean muscle mass rather than fat
Furthermore, the reduction in adipose tissue mass likely reduced obesity-associated systemic inflammation by reducing the release of pro-inflammatory adipokines, which can drive cartilage degeneration [80] and abnormal subchondral bone remodelling [81]
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