is semaglutide a diuretic and the Heart: Focus on Their Love–Hate Relationship Does Semaglutide Make You Pee – Semaglutide Reduces Need for Diuretics

Treatment should continue only if there is a clinically meaningful response (for example, HbA1c reduction 11 mmol/mol and weight loss 3% at around 6 months)

FEATURES DEXCOM G7 DEXCOM G6 Sensor Lifespan 10-day wear 10-day wear Grace-Period 12-hours None Warm-up Time 30 minutes 2 hours Accuracy (MARD) 8.2% 9% Transmitter All-in-one sensor and transmitter Separate G6 Transmitter Calibration No fingersticks required Requires 2 calibrations per day Size 60% smaller than G6, all-in-one integrated design Larger, two-piece system (transmitter and sensor) Dimensions W: 1.07 x L: 0.94 W: 1.2" x L: 1.8" Data Transmission Every 5 minutes, directly from sensor Every 5 minutes via transmitter Water Resistance Waterproof 2.4m - up to 24 hours Water resistance 2.4m - up to 24 hours Alarm Customization Quiet Mode, Delayed 1st Alert, Urgent Low Alert Customizable alerts Data Sharing Share data with up to 10 followers Share data with up to 10 followers Wearable Location Back of upper arm, Upper buttocks (children only 2-6 years) Abdomen, Upper buttocks (children only 2-17 years)

CV risk profile subgroups To assess the effect of baseline CV risk profiles on outcomes, two separate subgroup analyses were performed: (1) for subjects who had experienced a prior MI or stroke compared with those who had not, and (2) for those with established CVD, defined as prior stroke, ischemic heart disease (including MI), peripheral arterial disease, 50% arterial stenosis in any artery, coronary revascularization (percutaneous coronary intervention or coronary artery bypass graft), or heart failure vs those with CV risk factors alone and no manifestations of CVD as defined above

Important Safety Information What is the most important information I should know about Semaglutide