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Vehicle IGF-1 (5 nM) or IGF-2 (20 nM) was then added to the media for 2 min and cells were then rapidly lysed in ice-cold buffer to assess receptor activation as described below
It helps protect cells from oxidative stress, which occurs when unstable molecules called free radicals accumulate and damage healthy tissue
Oxidative stress can result either from the excessive production of reactive oxygen species, which might be anticipated at times of glutamatergic over-activity, or from a reduction in oxidative defences, and can damage cell structures
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