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HS disease activity was defined by treating clinicians' documentation and is reported as improvement, no change, or worsening disease

Alternatives to Semaglutide ( Ozempic) Ozempic, like Semaglutide, is a GLP-1 receptor agonist used to manage Type 2 diabetes

However, the authors did not provide images of morphologically identifiable synapses at the ultrastructural level

Gastrointestinal Side Effects The most common adverse events were gastrointestinal in nature, as expected for this drug class: Nausea the most frequently reported GI side effect, typically most pronounced during dose escalation and diminishing over time Diarrhea reported at moderate frequency Constipation less common than nausea but clinically relevant for some participants Vomiting generally mild and often transient These GI effects are mechanistically linked to GLP-1 receptor activation (slowed gastric emptying, central appetite suppression) and are a recognized feature of all GLP-1-based therapies