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2019 Apr;134:66677

PDRN inhibits melanogenesis through downregulation of microphthalmia-associated transcription factor (MITF), and the 2024 Tsai split-face RCT demonstrated significant melasma severity reduction with combined microneedling radiofrequency and depigmenting agents in Fitzpatrick III and IV patients

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Mahesh, T., Balasubashini, M