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Barbieri M, Paolisso G, Kimura M, Gardner JP, Boccardi V, Papa M, Hjelmborg JV, Christensen K, Brimacombe M, Nawrot TS: Higher circulating levels of IGF-1 are associated with longer leukocyte telomere length in healthy subjects
the apoptosis-regulating proteins Bcl-2 and Bax, the protein phosphatases PP2A and PPP1C, and the cell division control protein Cdc-42 [120]
It restores a more youthful GH pulse pattern without replacing growth hormone directly, it has a cleaner side effect profile than older secretagogues, and the effects on sleep, recovery, body composition, and skin compound over 8 to 12 weeks in a predictable way
Hypertrophy + hyperplasia Animal-model research shows IGF-1 LR3 drives both fibre growth (hypertrophy) and new fibre formation (hyperplasia) - distinct from most anabolic agents
