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Adding medication changes that curve substantially: Wegovy tablet: 13.6% average weight loss (OASIS 4 trial, 64 weeks) Wegovy injection: 14.9% average weight loss (STEP 1 trial, 68 weeks) Mounjaro Injection: up to 22.5% average weight loss at the highest dose (SURMOUNT-1 trial, 72 weeks) Sources: Wilding et al., NEJM 2021 (STEP 1) Wharton et al., NEJM 2025 (OASIS 4) Jastreboff et al., NEJM 2022 (SURMOUNT-1

In cases of suspected cobalt hypersensitivity, an intradermal test dose should be administered

Mounjaro and Wegovy are not interchangeable, so it is not recommended that you switch back and forth regularly, as this could affect your progress

This personalized approach guarantees that individuals receive tailored recommendations to address their specific needs and goals