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Through the analysis of numerous in vivo and in vitro studies aimed at determining the mechanisms by which GLP-1 enhances insulin secretion in individuals with normal glucose tolerance or T2DM, two main intracellular mechanisms underlying the incretin effect have emerged

Semaglutide: This is a powerful player in the realm of weight management medications that belongs to a class of drugs known as GLP-1 receptor agonists or GLP-1 for short

The STEP trials demonstrated that semaglutide produces dose-dependent weight loss, with higher doses showing greater average reductions

Dave Kisor from Manchester University College of Pharmacy (Fort Wayne, IN)