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Patients who have previously experienced an allergic reaction (such as anaphylaxis, angioedema, or urticaria) after MB administration should not be re-exposed
This schedule aligns with British practice, reflecting the longer duration of action of hydroxocobalamin

Neurotoxic Effects of Berberine on Long-Term L-DOPA Administration in 6-Hydroxydopamine-Lesioned Rat Model of Parkinson's Disease

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