8 Method-of-use and titration strategies Method-of-use patents often cover the titration schedulethe step-by-step increase in dosage intended to mitigate gastrointestinal side effects
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37 This can involve adding a small amount of weight, performing more repetitions within the target range (e.g., aiming for 15 reps instead of 12), adding another set, slightly reducing rest time, or moving to a more challenging exercise variation