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[3] The regulation of levels of ROS, levels of oxidized and reduced glutathione and other thiols, and antioxidant enzymes (such as GSTs and glutathione reductase) are important in determination of the most stable conditions for redox control, or for activation of apoptosis

NAC acts as a mediator of glutathione production and protects cells from damage

731 Pharmacological inhibition of USP14 effectively reduces the level of NCOA4 to protect neurons from ferritin-mediated ferroptosis