After significant weight loss, your resting metabolic rate drops slightly more than body-size change alone would predict, an effect called metabolic adaptation 8
The greatest weight loss benefits were observed when Tirzepatide was used in combination with lifestyle changes, such as improved diet and consistent exercise
the second is to prepare the drug into liquid and then carry out aseptic split charging directly, then carry on freeze drying, its advantage is that the difference of the charge is easy to control, can strengthen the stability of the drug, the disadvantage is for reduced glutathione, the condition of freeze drying is not easy to control, cause the rejection rate to be higher, even influence the stability of the drug in the valid period
There are also many other factors influencing the risk of developing obesity, including genetics, cultural factors, the characteristics of social and physical environments one lives in, and many others (e.g., Angl et al., 2009