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Cyclosporine also has a strong immunosuppressive effect, and many scholars have pointed out that this type of immunosuppressive agent can be used as the first choice for acute severe UC

HowickJKoletsiDIoannidisJPAMadiganCPandisNLoefMet al

Bone Health: It contributes to bone density and strength, playing a role in preventing osteoporosis

Pharmacological targeting of CHAC1-mediated processes therefore represents a rational therapeutic strategy, potentially disrupting the cycle of GSH depletion, ER stress amplification and iron-dependent peroxidation that drives neuronal loss

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