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Additionally, those with a history of pancreatitis, severe gastrointestinal disorders, or allergies to any components of the medication may not be good candidates

This imbalance of the gut microbiota and continued exposure of the colonic epithelial cells to urea is harmful to intestinal epithelial barrier function as it aids the disruption of the mucus layer and lowers the expression of tight junction proteins (Vaziri et al., 2013

[PMID: 3401252] PubMed record related to this compound for laboratory literature review

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