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383 SIRT5-catalyzed demalonylation and inactivation of SDHA block the TCA cycle and induce succinate accumulation, promoting tumorigenesis and drug resistance

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It directly donates a reducing equivalent (a hydrogen electron) to these unstable molecules, neutralizing them into harmless water and oxygen before they can wreak havoc on the cell's delicate machinery

In a study published in the Journal of Managed Care and Specialty Pharmacy, Sujith Ramachandran, associate professor of pharmacy administration, said that cost-effective does not necessarily mean cost-saving for insurance companies