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La glioxalasa I cataliza la conversin de glutatin metilglioxal y glutatin reducido a SD-lactoil-glutatin

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To conclude, in this report we have provided the first, to our knowledge, comprehensive biochemical analysis of a TGR selenoprotein from any organism , showing that it has remarkably wide substrate specificity and may be effectively inhibited by a number of low-molecular-weight compounds

558,559 However, SIRT1 and SIRT2 are generally reduced in ALS primary motor cortex while they are upregulated in the spinal cord in human post-mortem tissues