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The resulting Gly-His-Lys-Cu(II) complex shifts the peptide's behavior from a passive ligand to an active modulator of intracellular copper trafficking [2]

Estos incluyen efectos gastrointestinales como nuseas, vmitos y dolor abdominal, as como desmayos, dolor de cabeza, migraa, deshidratacin, pancreatitis aguda y clculos biliares

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Phase II clinical trials in patients with sarcoidosis-related small fiber neuropathy demonstrated significant increases in corneal nerve fiber density (a reliable surrogate marker for systemic small fiber health) alongside meaningful reductions in neuropathic pain scores