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Approximately 0.18% of the starting population survived and settled into a persister state characterized by drug tolerance and negligible growth ( Figures 1C, E )
Instead, these medications can be thought of as an adjunct to lifestyle changes like diet and exercise
Tolerability, safety and pharmacodynamics of oral, small-molecule glucagon-like peptide-1 receptor agonist danuglipron for type 2 diabetes: a 12-week, randomized, placebo-controlled, phase 2 study comparing different dose-escalation schemes
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