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Warnings Risk of Thyroid C-Cell Tumors In mice and rats, semaglutide caused a dose-dependent and treatment-duration-dependent increase in the incidence of thyroid C-cell tumors (adenomas and carcinomas) after lifetime exposure at clinically relevant plasma exposures

Potential Side Effects of Semaglutide Although Semaglutide is generally well-tolerated, it may cause side effects such as nausea, diarrhea, and constipation, particularly during the initial phase of treatment

Diarrhoea , in particular, may be exacerbated by the combination of altered bile flow and semaglutide's effects on gut motility

SattarNMcGuireDKPavoIWeerakkodyGJNishiyamaHWieseRJet alTirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis