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According to NICE guidance on diabetes management (NG28), any significant change in symptoms whilst on diabetes medication should be reviewed to ensure treatment remains appropriate and effective

33,34 Because acute kidney injury is associated with accelerated progression to chronic kidney disease and increased cardiovascular morbidity, careful evaluation of the renal safety of contemporary glucose-lowering and weight management therapies is essential

HGF phosphorylates MET, ERK, and AKT (Shin et al., 2017

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