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Its concurrent engagement of GLP-1R, GIPR, and GCGR distinguishes it structurally and pharmacologically from both selective GLP-1R agonists such as semaglutide and dual GLP-1R/GIPR agonists such as tirzepatide
1 Introduction The goal in growth-promoting therapy in children with growth disorders is to increase the child's growth rate and adult height while approaching a physiological pattern of growth hormone (GH) secretion
10.3389/fnins.2021.646678 77
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