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Regular check-ups are important to make sure the chosen dose is working well for each patient
The B12-intrinsic factor complex travels to the terminal ileum where specific receptors mediate absorption
Before starting B12 supplements , particularly high-dose formulations, discuss with your GP if you have: A history of sleep disorders Existing anxiety or mood disorders Cardiovascular conditions Kidney disease (which may affect B12 metabolism and test interpretation) Leber's hereditary optic neuropathy (cyanocobalamin is contraindicated
The restrictive diets that leave you exhausted and irritable
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