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They have emerged as key therapeutic targets in diabetes and obesity research, inspiring the development of dual and triple receptor agonists that synergistically enhance glycemic control, promote weight loss, and improve overall metabolic health [3]
a , b , Comparison of wild-type GLP-1R and the R176 2.46b Q mutant by GLP-1 binding assay ( a ) and functional cAMP accumulation assay ( b )
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