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The most common intraoperative complication reported is visceral injury (esophageal and gastric perforations), which is reported in up to 11% of cases, followed by vagal nerve injury and pulmonary complications (pneumonia) [23]

Earlier tirzepatide use outperforms other GLP-1s in type 2 diabetes A company-funded study found that recently diagnosed type 2 diabetes patients whose disease was not adequately controlled with metformin fared significantly better when tirzepatide was added to their regimen compared to other drugs in the GLP-1 class

On the other hand, melatonin dysregulation in bipolar disorder may be caused by light-sensitive melatonin suppression and delayed melatonin secretion [10]

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